Flow Granulocyte Adhesion Molecules Immune Deficiency Panel
CD11b (MAC-1) & CD18 Granulocyte Adhesion Molecules
CMH Lab Section
3 mL of blood in EDTA lavendar tube
Turn Around Time
Specimens must be <24 hours old when recieved in the Flow Cytometry Lab
Friday: Specimens must be drawn and recieved in the Flow Cytometry Lab before 1400.
Do NOT collect after 1400 Fridays or on weekends
Room temperature, do not refrigerate
Granulocytes are stimulated with Phorbol 12-Myristate 13-Acetate (PMA). Measurements of unstimulated and stimulated granulocytes are compared.
Testing measures the upregulation of CD11b & CD18 adhesion molecules which is useful in diagnosis of Leukocyte Adhesion Deficiency (LAD) or Lazy Leukocyte Syndrome.