Children's Mercy Hospitals and Clinics
Name
Allergic Broncho-Pulmonary Aspergillosis Algorithm

CMH Lab Section
Immunology

Specimen Requirements
3 mL blood in a red top wi/yellow ring gel tube

Availability
Routine

Turn Around Time
2-7 days
Portion of testing is batched and run on Tuesdays

Special Instructions
Algorithm: Total IgE: if >500 kU/L then Apergillus fumigatus IgE and IgG

Processing Instructions
Spin and refrigerate serum

Methodology
ImmunoCAP

Ranges
Aspergillus fumigatus IgE
Class 6 is ≥ 100 kU/L
Class 5 is ≥ 50 kU/L but < 100 kU/L
Class 4 is ≥ 17.5 kU/L but < 50 kU/L
Class 3 is ≥ 3.5 kU/L but < 17.5 kU/L
Class 2 is ≥ 0.7 kU/L but < 3.5 kU/L
Class 1 is ≥ 0.35 kU/L but < 0.7 kU/L
Class 0 is < 0.35 or absent or undetected

Aspergillus fumigatus IgG
> 2.0 mg/L indicates exposure
>50.0 mg/L is unusual

Total IgE
kU/L Age
<2-5.2 0 days
<2-5.2 14 days
<2-5.2 1 month
<2-9.2 3 months
<2-9.2 6 months
<2-16.4 9 months
<2-22.6 1 year
<2-29.2 2 years
<2-51.7 3 years
<2-51.7 4 years
<2-126 6 years
<2-160 8 years
<2-192 10 years
<2-127.2 12 years


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