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Kidney Transplant Research

Transplant research activities conducted at Children's Mercy are designed to improve the overall transplant experience and outcome for our patients.

Research Highlights

  • Evaluation of immunosuppressive dosing regimens as part of our quality improvement activities has resulted in modification of medication administration schedules and more prompt achievement of therapeutic drug levels. 
  • We are working with colleagues in the Center for Personalized Medicine and Therapeutic Innovation to explore the influence of genomic-based variations in patient drug metabolism characteristics on individualized treatment regimens.
  • Our program is a regular participant in national industry-sponsored pharmaceutical studies. Current protocols are addressing the use of erythropoietic stimulating agents, vitamin D and anti-viral agents in transplant recipients.
  • We are one of a select group of pediatric transplant programs in the country participating in a study sponsored by the National Institutes of Health of antihypertensive therapy in pediatric transplant patients.
  • The transplant, dialysis and general nephrology programs are active members of the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS). Activities include data entry into the transplant, dialysis and chronic kidney disease registries, participation in the benchmarking project, and frequent patient entry into prospective clinical trials.

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