- Allogeneic bone marrow transplant
- Marrow from an unrelated adult or pediatric donor is used.
- Synegeneic bone marrow transplant
- Marrow from an identical twin is used.
- Autologous bone marrow transplant
- The patient's own marrow is used.
- T-cell depleted transplants
- T-cells can sometimes attack
tissues after a transplant and cause graft versus
host disease (GvHD). To minimize this risk, specialists modify the
transplant before and after infusion by removing the T-cells.
- Nonmyeloablative transplants do not completely destroy the
patient's diseased marrow. In this transplantation procedure,
pediatric patients receive lower doses of chemotherapy or
- High-dose chemotherapy with autologous stem cell rescue
- This approach is used during a conditioning period to kill the
tumor. Bone marrow function is then restored by infusing the
patient's own previously stored bone marrow cells.
- Mismatched bone marrow transplantations for family members
- Children's Mercy Hospitals and Clinics is one of the few
centers in the U.S. equipped to provide this
- Mini transplants
- This approach uses the donor's immune system to reduce the
amount of chemotherapy needed for the transplant.
Commonly Treated Conditions
Pediatric Bone Marrow Transplantation services are for children
with a variety of childhood
- Leukemia and lymphoma
- Congenital hypoplastic anemia (failure of the bone marrow to
produce blood cells, including red and white blood cells and
- Solid childhood tumors
- Inherited disorders
We also offer Bone Marrow Transplantation services for Sickle Cell Disease,
Autoimmune Disorders, and other Hematologic